While most cases of infectious mononucleosis are debilitating, a few may be quite severe and even life-threatening.
Most cases of severe disease are associated with a first exposure to Epstein-Barr virus as an adult.
Criteria for severe infectious mononucleosis:
(1) hospitalization
(2) death
Reasons for hospitalization:
(1) cholestatic hepatitis
(2) severe hepatitis
(3) severe dysphagia
(4) hemophagocytic lymphohistiocytosis
(5) painful splenomegaly with or without rupture
(6) airway obstruction
(7) meningoencephalitis
(8) severe hemolytic anemia or pancytopenia
(9) myocarditis
(10) diffuse lymphoproliferative disorder
(11) multi-organ failure
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Purpose: To evaluate a patient with severe Epstein-Barr virus-related infectious mononucleosis.
Specialty: Infectious Diseases, Hematology Oncology
Objective: severity, prognosis, stage
ICD-10: B27,
