SWEDEHEART Score of Simonsson et al for Major In-Hospital Bleeding After Acute Myocardial Infarction

Description

Simonsson et al reported the SWEDEHEART score for predicting major in-hospital bleeding after an acute myocardial infarction. This can help to identify a patient at risk for major hemorrhage. The authors are from Karolinska Institute, Uppsala University, Linkoping University and the University of Leeds.

Patient selection: in-hospital, acute myocardial infarction, post-PCI or CABG

Outcome: fatal or intracranial bleeding, bleeding requiring transfusion or surgery

Parameters:

(1) hemoglobin in g/L and sex

(2) age in years

(3) serum CRP in mg/L

(4) serum creatinine in µmol/L

Hemoglobin in Male	Points
< 90	10
90 to 150	(0.0012067((Hgb)^2))-(0.45754(Hgb))+41.47
150 to 160	(0.04878*(Hgb)) - 7.317
160 to 170	(0.1 * (Hgb)) - 16
> 170	1.5

Hemoglobin and Female	Points
< 90	9
90 to 150	(0.0015625 ((Hgb)^2)) - (0.48302 (Hgb)) + 39.893
150 to 170	(0.0020596((Hgb)^2))-(0.57073(Hgb))+41.815
> 170	4.3

Age in Years	Points
< 40	0
40 to 70	(-0.001084 * ((age)^2)) + (0.21626 * (age)) - 6.9349
70 to 95	(-0.002122((age)^2)) + (0.28773 (age)) - 6.8576
> 95	1.4

Serum CRP	Points
0.1 to 10	(0.23487 * LOG10(CRP)) + 0.46973
10 to 235	(0.25324((LOG10(CRP))^2))+(0.41758(LOG10(CRP))) + 0.030794
> 235	2.4

Serum Creatinine	Points
< 40	0
40 to 80	(-0.0005187 * ((creat)^2)) + (0.10594 * (creat)) - 3.4061
80 to 345	(0.0017794 * (creat)) + 1.6083
> 345	2.2

total score =

= SUM(points for all 4 parameters)

Interpretation:

• minimum score: 0

• maximum score: 17.5

• The higher the score the greater the risk of major bleeding.

Total Score	Percent with Major Bleeding
< 6.2	< 0.5%
6.2 to 14.1	(0.020287 * ((score)^3)) - (0.42993 * ((score)^2)) + (3.3286 * (score)) - 8.4549
> 14.1	> 10%

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SWEDEHEART Score of Simonsson et al for Major In-Hospital Bleeding After Acute Myocardial Infarction

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