Survival Model of Hackbarth et al for Pediatric Patients with Brain Injury

Description

Hackbarth et al studied children with head injury and developed an equation by logistic regression for predicting survival. This can help identify children who require more aggressive therapy. The authors are from DeVos Children's Hospital, the Cook Research Institute, Mary Free Bed Rehabilitation Hospital and Michigan State University.

Patients: ages ranged from 1 month to 18 years

Parameters:

(1) minimum cerebral perfusion pressure (CPP) in mm Hg during day 1 (first 24 hours) in ICU

(2) bradycardia in the Emergency Department

Age	Heart Rate in the ED	Points
infant (< 1 year old)	< 80 beats per minute	1
	>= 80 beats per minute	0
1 – 18 years old	< 60 beats per minute	1
	>= 60 beats per minute	0

X =

= (-2.25 * (points for bradycardia in ED)) + (0.092 * (minimum CPP in mm Hg)) - 2.6

probability of survival =

= EXP(X) / (1 + EXP(X))

Keeping the cerebral perfusion pressure > 60 mm Hg improved survival significantly.

Performance:

• The predictive value of the score in the study set was 94%.

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Description

Specialty

ICD-10