Description

Schmidt et al reported the SAVE (Survival After Veno-Arterial ECMO) score for predicting survival in a patient with refractory cardiogenic shock treated with extracorporeal membrane oxygenation (ECMO). The authors are from Monash University, Universite Pierre et Marie Curie, Alfred Hospital, Extracorporeal Life Support Organization, Chidlren's Hospital Boston, Harvard Medical School and Columbia College of Physicians and Surgeons.


Patient selection: refractory cardiogenic shock, age >= 18 years

 

Parameters:

(1) acute cardiogenic diagnosis (5 items)

(2) age in years

(3) weight in kilograms

(4) acute pre-ECMO organ failures (3 items)

(5) chronic renal failure

(6) duration of intubation prior to initiation of ECMO in hours

(7) peak inspiratory pressure in cm H2O

(8) pre-ECMO cardiac arrest

(9) diastolic blood pressure prior to ECMO in mm Hg

(10) pulse pressure prior to ECMO in mm Hg

(11) serum bicarbonate prior to ECMO in mmol/L

 

Parameter

Finding

Points

myocarditis

no

0

 

yes

3

refractory VT or VF

no

0

 

yes

2

after heart or lung transplantation

no

0

 

yes

3

congenital heart diseaes

no

0

 

yes

-3

other diagnosis causing shock

no

0

 

yes

0

age in years

18 to 38 years

7

 

39 to 52 years

4

 

53 to 62 years

3

 

>= 63 years

0

weight in kilograms

< 65 kilograms

1

 

65 to 89 years

2

 

>= 90 years

0

acute liver failure

no

0

 

yes

-3

acute CNS dysfunction

no

0

 

yes

-3

acute renal failure

no

0

 

yes

-3

chronic renal failure

no

0

 

yes

-6

duration of intubation

<= 10 hours

0

 

11 to 29 hours

-2

 

>= 30 hours

-4

peak inspiratory pressure

<= 20 cm H2O

3

 

> 20 cm H2O

0

pre-ECMO cardiac arrest

no

0

 

yes

-2

diastolic blood pressure before ECMO

>= 40 mm Hg

3

 

< 40 mm Hg

0

pulse pressure before ECMO

> 20 mm Hg

0

 

<= 20 mm Hg

-2

bicarbonate before ECMO

<= 15 mmol/L

-3

 

> 15 mmol/L

0

 

total score =

= SUM(points for all of the parameters) -6

 

Interpretation:

minimum score: -35

maximum score: 17

The higher the score the better the survival.

 

Score

Risk Class

Survival

>= 6

I

75%

1 to 5

II

58%

-4 to 0

III

42%

-9 to -5

IV

30%

<= -10

V

18%

 


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