Johnson described 3 types of gastric ulcers based on location and pathogenesis. A fourth type was reported by Csendes et al.
Location: Ulcers tend to occur at junctions between different mucosal types (oxyntic-antral, antral-pyloric, esophago-gastric).
Location |
Acid Production |
Type |
body of stomach |
low to normal |
I |
body of stomach and duodenum |
increased |
II |
prepyloric or pyloric (within 2 cm of pylorus) |
increased |
III |
subcardial or juxtacardial (within 4 cm of squamocolumnar junction) |
low to normal |
IV |
where:
• Type II or III ulcerations may be treated with vagotomy because of acid hypersecretion.
• Type III ulcers are also referred to as pyloric channel ulcers.
Type |
Associations |
I |
diffuse antral gastritis or multifocal atrophic gastritis |
II |
perforation or obstruction |
III |
perforation or obstruction |
IV |
massive or recurrent bleeding, deep penetrating ulcer without perforation, slow gastric emptying |
Specialty: Gastroenterology, Infectious Diseases, Surgery, general