The Standardization of Uveitis Nomenclature (SUN) Working Group reported criteria for Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE).

APMPPE is a posterior uveitis with lesions at the level of the retinal pigment epithelium and choroid.


Criteria for APMPPE - all of the following:

(1) paucifocal or multifocal choroidal lesions

(2) lesions appear plaque-like or placoid appearance

(3) characteristic fluorescein angiogram in the acute phase

(4) negative for syphilis and sarcoidosis


On fluorescein angiography the lesions are hypofluorescent early and hyperfluorescent late.

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