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Description

A patient with Parkinson's Disease may experience a sudden, unexpected death. In many cases the immediate cause of death may not be readily apparent.


Some patients with Parkinson's disease develop a cardiac autonomic dysfunction, which may be associated with a prolonged QTc interval. The presence of a prolonged QTc may be associated with a fatal arrhythmia, sometimes triggered by medications.

 

Other risk factors:

(1) sleep apnea

(2) adverse drug effects not associated with QTc prolongation

(3) coronary artery disease

(4) cardiomyopathy

(5) cardiac arrhythmias not associated with QTc prolongation

 

Differential diagnosis:

(1) suicide

(2) cerebrovascular disease

(3) pneumonia


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