The Subjective Peripheral Neuropathy Screen (SPNS) is a brief, self-reporting screening tool for peripheral neuropathy. It has been used by the National Institute of Allergy and Infectious Diseases to evaluate patients with AIDS for sensory neuropathy.



Ask the patient to rate the severity of each symptom on a scale of 1 (mild) to 10 (most severe). Enter the score for each symptom in the column marked Presence/Severity. If symptoms have been present in the past, but not since the last visit, enter "currently absent". If the symptom has never been present, enter "always been normal".



(1) pain, aching, or burning in hands, arms

(2) pain, aching, or burning in feet, legs

(3) "pins and needles" in hands, arms

(4) "pins and needles" in feet, legs

(5) numbness (lack of feeling) in hands, arms

(6) numbness (lack of feeling) in feet, legs


Recorded severity for each symptoms:

(1) never, always been normal

(2) currently absent

(3) if currently present, assigned a score from 1 (mild) to 10 (most severe)

Maximum Severity Score

Grade of Neuropathy

never or currently absent


1 – 3


4 – 6


7 – 10



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