Description

Subclinical rejection refers to a slowly progressing rejection that is asymptomatic yet destructive to the transplanted organ.


Patient selection: transplant recipient

 

Clinical features:

(1) absence of significant clinical symptoms

(2) deterioration in function of the transplanted organ over time if untreated

(3) evidence of chronic inflammation in a biopsy from the transplanted organ taken shortly after the transplant, with later fibrosis

(4) reduced graft survival


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