Eleid et al studied the relationship between the stroke volume index and mortality for patients with severe aortic stenosis, a normal ejection fraction and low gradient. A number of risk factors may contribute to mortality. The authors are from the Mayo Clinic.
Patient selection: low-gradient severe aortic stenosis with normal ejection fraction
stroke volume index =
= (stroke volume) / (body surface area)
SVI in mL per sq meter
Annualized Mortality Rate
> 45
7.4
40 to 45
10.3
35 to 40
11.1
30 to 35
19.2
< 30
25.1
Other predictors from the multivariate analysis:
(1) older age (HR 1.05)
(2) body mass index (HR 0.92)
(3) right ventricular systolic pressure in mm Hg (HR 1.03)
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