Sterile peritoneal fluid eosinophilia, also termed eosinophilic peritonitis, may occur in patients undergoing peritoneal dialysis. It is important to distinguish from infectious peritonitis and other conditions associated with increased eosinophils in the peritoneal fluid.


Diagnostic features:

(1) episodic abdominal discomfort

(2) absence of fever or chills

(3) absence of abdominal rigidity or tenderness

(4) cloudy peritoneal effusion

(5) peritoneal fluid eosinophil count > 100 per µL, or > 10% of the fluid WBC count

(6) eosinophilia in the peripheral blood often, usually mild

(7) cultures of the peritoneal fluid negative

(8) negative history for hypereosinophilic syndrome, parasitic infestation, allergic disease, polyserositis, immunodeficiency, connective tissue disorder, vasculitis, tuberculosis or malignancy


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