StenoSCORE of Karaba et al for Predicting Stenotrophomonas maltophilia Bloodstream Infection in a Patient with a Hematologic Malignancy: Risk Score 1 (Knowledge-Driven)
Karaba et al reported the StenoSCORE for predicting bloodstream infection with Stenotrophomonas maltophilia in a patient with a hematologic malignancy. There are 2 versions of the score - one knowledge-driven and the second based on automatic variable selection. The authors are from Johns Hopkins University.
Patient selection: hematologic malignancy, age >= 12 years
Parameters for knowledge-driven score:
(1) acute leukemia
(2) absolute neutrophil count per microliter
(3) mucositis
(4) central venous catheter
(5) number of days with receipt of carbapenem
Parameter
Finding
Points
acute leukemia
no
0
yes
1
absolute neutrophil count
< 100 per µL
0
100 to 499 per µL
3
500 to 999 per µL
6
1,000 to 1,499 per µL
9
>= 1,500 per µL
12
mucositis
no
0
yes
23
central venous catheter
absent
0
present
22
carbapenem receipt
none or < 3 days
0
>= 3 days
19
total score =
= SUM(points for all parameters)
Interpretation:
• minimum score: 0
• maximum score: 77
• A score >= 41 had a sensitivity of 0.38 and specificity 0.87.
• A score of >= 27 had the highest Youden score (0.42)..
Performance:
• The area under the ROC curve is 0.75.
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