STATE Score of Hucke et al for a Patient with Hepatocellular Carcinoma

 

STATE is an acronym for Selection of TrAnsarterial chemoembolization TrEatment with TransArterial ChemoEmbolization referred to as TACE.

 

Patient selection: intermediate stage HCC (Child-Pugh A or B cirrhosis, asymptomatic, large or multifocal, without macrovascular invasion or extrahepatic metastases)

 

Parameters:

(1) serum albumin in g/L

(2) up-to-seven criteria

(3) C-reactive protein (CRP) in mg/dL

Parameter	Finding	Points
up-to-seven criteria	met	0
	exceeds (beyond)	-12
CRP	< 1 mg/dL	0
	>= 1 mg/dL	-12

 

STATE score =

= (serum albumin) + (points for up to seven) + (points for CRP)

 

Interpretation:

• A STATE score >= 18 was associated with a median overall survival of 19.5 months.

• A STATE score < 18 was associated with a median overall survival of 5.3 months.