Karadaghy et al reported staging systems for patients with nonmetastatic papillary thyroid carcinoma. The first deals with the functional status of the patient, designated the Functional Severity Staging System (FSSS). The authors are from the University of Missouri in Kansas City and Washington University in St. Louis.
Patient selection: nonmetastatic papillary thyroid carcinoma, >= 18 years of age
Parameters:
(1) age in years
(2) comorbidity by the ACE-27
Age in Years
Comorbidity
FSSS
18 to 39 years
none
alpha
mild
alpha
moderate or severe
alpha
40 to 49 years
none
alpha
mild
alpha
moderate or severe
alpha
50 to 59 years
none
alpha
mild
beta
moderate or severe
beta
60 to 69 years
none
alpha
mild
beta
moderate or severe
gamma
>= 70 years
none
beta
mild
beta
moderate or severe
gamma
The FSSS is combined with the tumor T stage to derive the clinical severity scoring system (CSSS).
FSSS
5-Year Overall Survival
alpha
96%
beta
80%
gamma
57%
Performance:
• The area under the ROC curve was 0.80 for the Siteman Registry and 0.71 for NCDB data.
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