Karadaghy et al reported staging systems for patients with nonmetastatic papillary thyroid carcinoma. The first deals with the functional status of the patient, designated the Clinical Severity Staging System (CSSS). The authors are from the University of Missouri in Kansas City and Washington University in St. Louis.
Patient selection: nonmetastatic papillary thyroid carcinoma, >= 18 years of age
Parameters:
(1) T stage
(2) functional severity stage of the FSSS
T stage
FSSS
CSSS
T1 or T2
alpha
A
beta
A
gamma
B
T3
alpha
A
beta
B
gamma
C
T4
alpha
A
beta
B
gamma
C
The CSSS correlates with 5-year overall survival.
CSSS
5-Year Overall Survival
A
94%
B
67%
C
45%
Performance:
• The area under the ROC curve was 0.74 for the Siteman Registry and 0.62 for NCDB data
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