Yueh et al reported a staging system for recurrent, persistent and secondary primary cancers in the oral cavity or oropharynx. The authors are from the University of Washington, Veterans Affairs Puget Sound Health Care System, Yale University and Veterans Affairs Connecticut Health Care System.
Patient selection: persistent, recurrent or new cancer in the oral cavity or oropharynx (persistent if evident at site of primary less than 3 months after therapy completed; recurrent if evident at site of primary 3 or more months after therapy completed; second if at a different site)
Parameters:
(1) TNM status
(2) weight loss
(3) muscle invasion
(4) metastases
TNM
Weight Loss
Muscle Invasion
Metastases
Stage
<= T2N0M0
none
none
none
A
<= T2N0M0
< 20%
none
none
B
> T2N0M0
none
none
none
B
<= T2N0M0
>= 20%
none
none
C
> T2N0M0
any
none
none
C
NA
NA
present
NA
D
NA
NA
NA
present
D
Stage
1-Year Survival
A
88%
B
72%
C
33%
D
4.2%
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