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Description

Gillmore et al reported a staging system for transthyretin-associated cardiac amyloidosis. This can help to identify a patient who may benefit from more aggressive management. The authors are from University College London, Henri Mondor Teaching Hospital and Eastman Dental Institute.


Patient selection: cardiac amyloidosis due to transthyretin

 

Parameters:

(1) NT-proBNP in ng/L

(2) eGFR in mL per min per 1.73 square meters

 

Parameter

Finding

Points

NT-proBNP

<= 3,000 ng/L

0

 

> 3,000 ng/L

1

eGFR

>= 45 mL/min/1.73 sq m

0

 

< 45 mL/min/1.73 sq m

1

 

total score =

= SUM(points for both parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 2

 

Score

Stage

Median Survival

0

I

69.2 months

1

II

46.7 months

2

III

24.1 months

 


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