Ficarra et al proposed a staging system for locally advanced renal cell carcinoma. The authors are from multiple hospitals in Europe.
Parameters:
(1) renal vein thrombosis
(2) invasion of perinephric fat
(3) thrombosis of infradiaphragmatic vena cava
(4) invasion of the ipsilateral adrenal gland
(5) thrombosis of supradiaphragmatic vena cava
(6) invasion of Gerota's fascia
Finding |
Proposed T Score |
Mean Survival if N0M0 |
renal vein thrombosis (1) |
pT3a |
117 months |
invasion of perinephric fat (2) |
pT3a |
98 months |
thrombosis of infradiaphragmatic vena cava (3) |
pT3a |
67 months |
invasion of ipsilateral adrenal gland (4) |
pT3b |
24 months |
invasion of perinephric fat AND renal vein thrombosis (1 + 2) |
pT3b |
24 months |
invasion of perinephric fat AND thrombosis of infradiaphragmatic vena cava (2 + 3) |
pT3b |
24 months |
invasion of adrenal gland AND renal vein thrombosis (1 + 4) |
pT4 |
11 months |
invasion of adrenal gland AND thrombosis of infradiaphragmatic vena cave (3 + 4) |
pT4 |
11 months |
thrombosis of supradiaphragmatic vena cava (5) |
pT4 |
12 months |
invasion of Gerota's fascia (6) |
pT4 |
12 months |
Specialty: Hematology Oncology, Surgery, general, Nephrology
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