The 8th Edition of the American Joint Commission on Cancer (AJCC) Staging Manual helps in the staging of an anaplastic thyroid carcinoma.
Patient selection: anaplastic thyroid carcinoma
Parameters (based on 8th Edition of the Staging Manual):
(1) T code
(2) N code
(3) M code
T Code
N Code
M Code
Stage
T1 to T3a
N0, NX
M0
IVA
T1 to T3a
N1
M0
IVB
T3b
any N
M0
IVB
T4
any N
M0
IVB
any T
any M
M1
IVC
where:
• T1 to T3a are limited to the thyroid gland.
• N1 indicates metastases to regional lymph nodes.
If gross extrathyroidal extension (T3b, T4) or regional lymph node metastasis (N1) are combined this could be simplified to (not part of the AJCC guidance):
Distant Metastases
Beyond Thyroid
Stage
Yes (M1)
NA
IVC
No (M0)
Yes (T3b, T4, N1)
IVB
No
No (T1 to T3a)
IVA
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