Sandrini et al reported criteria for staging adrenocortical tumors in children. The authors are from Federal University of Parana in Brazil, St. Jude Children's Research Hospital and the University of Tennessee.
Parameters:
(1) distant metastases
(2) resection
(3) volume
(4) hormone levels after surgery
(5) tumor spillage during surgery
Findings
Stage
distant metastases
IV
inoperable tumor OR gross residual tumor after resection
III
all of the following:
(1) tumor volume <= 200 cubic cm
(2) tumor completely excised at surgery
(3) normal hormone levels after surgery
(4) no tumor spillage during surgery
(5) no metastases
I
all other combinations
II
where:
• If the tumor is a sphere, 200 cubic cm approximates a diameter of 7.25 cm.
• In Table 3, Stage I has a tumor size of < 200 cubic cm and Stage II has a tumor size > 200 cubic cm. I made a tumor = 200 cubic cm as Stage I.
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