A patient with Hodgkin's disease can be staged based on clinical extent, pathologic findings and symptoms.
Parameters:
(1) clinical stage
(2) pathologic stage
(3) B symptoms (unintended weight loss > 10% over 6 months, night sweats, unexplained fever > 38°C).
Clinical Stage
Involvement
Stage
single lymph node region
I
single extralymphatic organ or site
IE
2 or more lymph node regions on the same side of the diaphragm
II
extralymphatic organ or site AND >= 1 lymph node group on the same side of the diagram
IIE
lymph node regions involved on both sides of the diaphragm
III
lymph node regions involved on both sides of diaphragm AND extralymphatic site
IIIE
lymph node regions involved on both sides of the diaphragm AND spleen involved
IIIS
lymph node regions involved on both sides of the diaphragm AND spleen involved AND extralymphatic site
IIISE
diffuse or disseminated involvement of one or more extralymphatic organs or tissues
IV
Pathologic Stage
Presence of involvement in a tissue is indicated by "+" while absence is indicated by "-".
Site
Designation
lymph node
N
liver
H
spleen
S
lung
L
bone marrow
M
pleura
P
osseous (bone)
O
dermal (skin)
D
Symptoms
If any B symptoms are present, then the patient is designated B.
If no B symptoms are present, then the patient is designated A.
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Specialty: Hematology Oncology
