SS2 Score of Mor et al for the Clinical Severity of Familial Mediterranean Fever (FMF)

Mor et al reported a severity score for evaluating a patient with familial Mediterranean fever (FMF).

Patient selection: familial Mediterranean fever

Parameters:

(1) number of sites affected during a single attack (in at least 25% of attacks)

(2) number of sites affected during the course of the disease

(3) number of pleuritic attacks during the course of the disease

(4) number of erysipelas-like attacks during the course of the disease

(5) age at onset in years

(6) dose of colchicine

Parameter	Finding	Points
number of sites during a single attack	< 2	0
	>= 2	1
number of sites in the course of the disease	<= 2	0
	> 2	1
number of pleuritic attacks	< 2	0
	>= 2	1
number of erysipelas-like attacks	< 2	0
	>= 2	1
age at onset	<= 10 years	1
	> 10 years	0
dose of colchicine	less than appropriate dose	0
	appropriate dose	1
	more than appropriate dose	2

where:

• The appropriate starting dose of colchicine is age-dependent (0.5 mg/day if < 5 years old; 1.0 mg/day if 5-10 years old; 1.5 mg/day if > 10 years)

total score =

= SUM(points for all 6 parameters)

Interpretation:

• mnimum score: 0

• maximum score: 7

• The higher the score the greater the disease severity.

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