A parathyroid adenoma or hyperplastic nodule may undergo spontaneous hemorrhage, a condition sometimes referred to as parathyroid apoplexy.


Acute hemorrhage may be the first indication of a parathyroid disorder, or it may occur in a known lesion.


Clinical manifestations depend on the location of the parathyroid hemorrhage and its severity.


Hemorrhage into a parathyroid lesion in the neck may be associated with:

(1) pain in the anterior neck

(2) bruising over the neck

(3) cough

(4) dysphagia

(5) shortness of breath


Hemorrhage into an ectopic focus of parathyroid tissue can result in mediastinal or thoracic hemorrhage.


There is often a change in serum calcium (may rise or fall).


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