SNACOR Score of Kim et al for a Patient Undergoing Chemoembolization for Hepatocellular Carcinoma

Description

Kim et al reported the SNACOR score for evaluating a patient undergoing transarterial chemoembolization (TACE) of a hepatocellular carcinoma. This can help to identify a patient who may benefit from more aggressive or an alternative therapy. The authors are from Yonsei University and University of Ulsan.

Synonym: SNACOR (size, number, AFP, Child-Pugh, objective response)

Patient selection: transarterial chemoembolization of a hepatocellular carcinoma

Parameters:

(1) tumor size in cm

(2) tumor number

(3) baseline AFP level in ng/mL

(4) Child-Pugh class

(5) objective radiological response

Parameter	Finding	Points
size	< 5 cm	0
	>= 5 cm	1
tumor number	< 4	0
	>= 4	2
baseline AFP	< 400 ng/mL	0
	>= 400 ng/mL	3
Child Pugh class	A	0
	B	1
response	complete or partial response	0
	stable or progressive disease	3

total score =

= SUM(points for all 5 parameters)

Interpretation:

• minimum score: 0

• maximum score: 10

• The higher the score the worse the prognosis.

Total Score	Risk	Median Overall Survival
0 to 2	low	50 months
3 to 6	intermediate	31 months
7 to 10	high	12 months

Performance:

• The area under the ROC curve was 0.75 for 3 year and 0.81 for 6 year overall survival.

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SNACOR Score of Kim et al for a Patient Undergoing Chemoembolization for Hepatocellular Carcinoma

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