Migraine attacks may start during sleep for some migraineurs.

Criteria: >= 75% of migraine attacks occur during sleep and/or upon awakening (onset during sleep causes wakening)


Inclusion for the study of Vollono et al required >= 5 headaches per month.


Migraine attacks:

(1) occur without aura

(2) tend to increase with age


A patient with sleep-related migraine shows a significant reduction of the ratio of low-frequency oscillatory components (LF) to high-frequency oscillatory components (HF) in spectral analysis of heart rate variability. This is a measure of dysfunction in the autonomic nervous system.


A different phenomenon is the relief of a migraine attack by falling asleep.

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