Ettinger et al reviewed skin conditions associated with primary immunodeficiencies.
The authors are from University Medical Center Regensburg and University Hospital of Cologne.
Patient selection: primary immunodeficiency and mycobacterial skin infection (often due to an atypical mycobacteria)
Conditions to consider include:
(1) GATA2 defects (GATA2)
(2) interferon-gamma R1/2 defects (IFNGR1/2)
(3) IRF8 defects (IRF8)
(4) ISG-15 disease (ISG15)
(5) macrophage gp91 phox defect (CYBB)
(6) Mendelian susceptibility to mycobacterial disease (MSMD; IFNGR1/2, IL1 2B/RB1)
(7) NEMO (X-linked ectodermal dysplasia with immunodeficiency; NEMO)
(8) STAT1 defect (STAT1)
