Ettinger et al reviewed skin conditions associated with primary immunodeficiencies. One such pattern is eczema. The authors are from University Medical Center Regensburg and University Hospital of Cologne.
Patient selection: primary immunodeficiency with eczema
Skin Appearance
Gene Mutation
Syndrome
eczema with allergy
SPINK5
Comel-Netherton syndrome
neonatal papulopustular eruption with later eczema
STAT3
Hiob/Job's syndrome (autosomal dominant HIES)
neonatal papulopustular eruption with later eczema, driven by food allergy
DOCK8
autosomal recessive HIES
neonatal eczema
WAS
Wiskott-Aldrich syndrome
erythematous indurated papules and plaques with central atrophy or ulcer
