Patient selection: neonate undergoing phototherapy for hyperbilirubinemia
Parameters:
(1) serum total bilirubin in mg/dL at start of phototherapy
(2) serum total bilirubin in mg/dL at end of phototherapy
(3) gestational age in weeks
drop in serum total bilirubin =
= (initial bilirubin) - (final bilirubin)
|
Parameter
|
Finding
|
Points
|
|
gestational age
|
>= 38 weeks
|
0
|
|
|
< 38 weeks
|
15.5
|
|
drop in bilirubin
|
|
- 4.3 * (drop)
|
total score =
= SUM(points for both parameters)
Interpretation:
• minimum score: negative score (depends on bilirubin drop)
• maximum score: 15.5
X =
= (0.097 * (score)) - 2.84
probability of rebound hyperbilirubinemia =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.88.
