Granholm et al reported the Simplified Mortality Score for the Intensive Care Unit (SMS-ICU) for predicting short-term mortality for a critically-ill patient. The authors are from Copenhagen University Rigshospitalet and the University of Copenhagen in Denmark.
Patient selection: unplanned admission, age >= 18 years
Outcome: 90-day mortality
Parameters:
(1) age in years
(2) lowest systolic blood pressure (minimum)
(3) type of admission
(4) cancer diagnosis
(5) use of inotropes/vasopressors
(6) use of respiratory support
(7) use of renal replacement therapy
Parameter
|
Finding
|
Points
|
age in years
|
<= 39 years
|
0
|
|
40 to 59 years
|
5
|
|
60 to 79 years
|
10
|
|
>= 80 years
|
13
|
lowest systolic blood pressure
|
<= 49 mm Hg
|
6
|
|
50 to 69 mm Hg
|
5
|
|
70 to 89 mm Hg
|
3
|
|
>= 90 mm Hg
|
0
|
admission
|
medical (acute, non-surgical)
|
3
|
|
other
|
0
|
cancer diagnosis
|
hematologic malignancy
|
7
|
|
metastatic cancer
|
7
|
|
localized cancer
|
0
|
|
no cancer
|
0
|
inotropes or vasopressors
|
no
|
0
|
|
yes
|
4
|
respiratory support
|
no
|
0
|
|
yes
|
5
|
renal replacement therapy
|
no
|
0
|
|
yes
|
4
|
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 42
• The higher the score the greater the risk of mortality.
In the study of Zampieri et al, the following mortality prediction equation was reported:
value of X =
= (0.21 * (score)) - 4.80
probability of mortality =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.72.