The fibrosis associated with asbestosis can be graded using a simplified version of the CAP-NIOSH criteria.
Specimens: larger pieces of tissue from thoracoscopy, lobectomy or pneumonectomy
Histologic Features
Grade
peribronchial fibrosis involving 0 to 49% of bronchioles
0
peribronchial fibrosis in >= 50% of bronchioles on a slide, with fibrosis confined to the bronchial walls and the first adjacent tier of alveoli
1
extension of fibrosis beyond the first tier of adjacent alveoli with sparing of some alveoli between adjacent respiratory bronchioles
2
fibrotic thickening in the walls of all alveoli between 2 or more adjacent respiratory bronchioles
3
honeycomb lung
4
If more than one slide is examined:
average grade =
= SUM(grades for all slides examined) / (number of slides examined)
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Specialty: Toxicology, Emergency Medicine, Critical Care
