The American College of Physicians (ACP) identified signs and symptoms that warrant red blood transfusion in an anemic, normovolemic patient.


Signs and symptoms that may be produced by anemia:

(1) syncope

(2) dyspnea

(3) postural hypotension

(4) tachycardia

(5) angina

(6) transient ischemic attack (TIA)


Reasons not justifying transfusion in the absence of the above:

(1) hypovolemia potentially responsive to crystalloid infusion

(2) correction of anemia due to iron, folate or vitamin B12 deficiency

(3) to provide a general sense of well-being

(4) prophylactic in the absence of significant risk for myocardial or cerebrovascular ischemia

(5) to promote wound healing


To read more or access our algorithms and calculators, please log in or register.