Some patients with sickle cell retinopathy may develop macular ischemia or infarction.
Clinical features:
(1) The patient has significant sickle cell disease (SS, SC, etc).
(2) The patient may or may not experience ocular pain.
(3) The patient experiences a loss of central visual acuity in one or both eyes.
Fundoscopy with angiography can demonstrate occlusion in small retinal arterioles as well as damage to the macula.
Some patients have responded to early erythrocytopheresis or exchange transfusion.
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Specialty: Ophthalmology, Hematology Oncology
