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Sib Method for Correction of Single Ascertainment

Specialty:

Genetics

Objective:

ICD-10:

Description:

In single ascertainment a random small sample of all cases in the population are identified. Examples include identifying the affected children in a clinic or school grade. For single ascertainment the probability that a family will be identified increases with the number of affected offspring. The sib method is used to correct the segregation ratio for the bias of single ascertainment.

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