This is a screening tool for differentiating heterozygous beta-thalassemia from healthy subjects. It cannot discriminate between beta-thalassemia and iron deficiency.

Shine-Lal formula =

= (((MCV)^2) * (MCH)) / 100



• MCV is the mean corpuscular volume as measured in femtoliters

• MCH is the mean corpuscular hemoglobin as measured in picograms



• thalassemia minor: < 1530.

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