Chen et al reported findings associated with the severity of hemorrhagic fever with renal syndrome (HFRS) due to a Hantavirus infection. The authors are from Xi'an Jiaotong University, Fudan University and Shanghai University of Traditional Chinese Medicine in China.
Patient selection: nonfebrile stage of hantavirus-associated hemorrhagic fever with renal syndrome
Parameters:
(1) body temperature in °C
(2) bleeding
(3) shock
(4) renal damage
(5) signs and symptoms of toxicity
Parameter
Finding
Severity
body temperature
< 39°C
mild
39 to 39.9°C
moderate
>= 40°C
severe
bleeding
petechiae
mild
ecchymosis
moderate
cavity hemorrhage
severe
shock
none
mild
hypotension
moderate
obvious shock
severe
renal damage
no oliguria; urine protein less than 2+
mild
oliguria; urine protein 2+ or greater
moderate
anuria
severe
toxicity
none to mild
mild
bulbar conjunctival edema
moderate
severe; psychological symptoms secondary to toxicity
severe
Criteria for critical disease - severe disease with one or more of the following:
