Description

Eisner et al reported the Severity of Asthma (SOA) score for patients with moderate to severe persistent asthma. It can help to identify a patient at increased risk for adverse clinical outcomes. The authors are from Genetech, Inc, in San Francisco.


Parameters:

(1) symptoms during the past 2 weeks

(2) use of systemic corticosteroids ever

(3) use of systemic corticosteroids in past year

(4) use of systemic corticosteroids >= 3 months during the past 2 years

(5) use of inhaled beta-agonists (SABA/LABA) during the past 2 weeks

(6) inhaled corticosteroids (ICS) by metered dose inhaler during the past 2 weeks

(7) cromolyn/nedocromil during the past 2 weeks

(8) anticholinergic therapy during the past 2 weeks

(9) theophylline, oral beta-agonist or leukotriene modifier during the past 2 weeks

(10) antihistamine, decongestant or nasal spray during the past 2 weeks

(11) home nebulizer use during the past 2 weeks

(12) ever hospitalized for asthma

(13) ever intubated for asthma

 

Parameter

Finding

Points

symptoms

none

0

 

minimal

1

 

occasional

2

 

most days or nights

3

 

every day or night

4

systemic corticosteroids ever

no

0

 

yes

2

systemic corticosteroids in past year

no

0

 

yes

2

systemic corticosteroids >= 3 months in past 2 years

no

0

 

yes

3

inhaled beta-agonists

none

0

 

< 2 puffs per day

1

 

>= 2 puffs per day

2

ICS

none

0

 

< 20 puffs per day

1

 

>= 20 puffs per day

2

cromolyn/nedocromil

no

0

 

yes

1

anticholinergic therapy

no

0

 

yes

1

theophylline, oral beta-agonist, leukotriene modifier

no

0

 

yes

1

antihistamine, decongestant or nasal spray

no

0

 

yes

1

home nebulizer

no

0

 

yes

1

ever hospitalized for asthma

no

0

 

yes

3

ever intubated for asthma

no

0

 

yes

5

 

total score =

= SUM(points for all 13 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 28

• The higher the score the more severe the asthma and the worse the clinical outcomes.


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