Kuo et al reported a score for predicting severe vitamin D deficiency in a patient in the intensive care unit (ICU). This can help to identify a patient who should be evaluated for vitamin D deficiency and a patient who may benefit from vitamin supplements. The authors are from multiple institutions in Taiwan.
Patient selection: patient in the ICU
Parameters:
(1) age in years
(2) mean arterial pressure in mm Hg
(3) serum albumin in g/dL
(4) heart rate in beats per minute
(5) gender
(6) sepsis
(7) postoperative status
(8) season of the year
Parameter |
Finding |
Points |
age in years |
< 55 |
7 |
|
55 to 59 |
6 |
|
60 to 64 |
4 |
|
65 to 69 |
2 |
|
70 to 74 |
1 |
|
75 to 79 |
0 |
|
80 to 84 |
1 |
|
85 to 89 |
2 |
|
90 to 94 |
3 |
|
>= 95 |
4 |
mean arterial pressure |
< 60 |
0 |
|
60 to 69 |
1 |
|
70 tp 79 |
2 |
|
80 to 89 |
3 |
|
90 to 99 |
4 |
|
100 to 109 |
5 |
|
110 to 119 |
6 |
|
120 to 129 |
7 |
|
>= 130 |
8 |
serum albumin |
< 1.5 |
10 |
|
1.5 to 1.9 |
9 |
|
2.0 to 2.4 |
8 |
|
2.5 to 2.9 |
6 |
|
3.0 to 3.4 |
5 |
|
3.5 to 3.9 |
3 |
|
4.0 to 4.4 |
2 |
|
>= 4.5 |
0 |
heart rate |
< 75 |
4 |
|
75 to 79 |
5 |
|
80 to 84 |
6 |
|
85 to 89 |
8 |
|
90 to 94 |
9 |
|
95 to 99 |
10 |
|
100 to 109 |
9 |
|
110 to 114 |
8 |
|
115 to 119 |
6 |
|
120 to 124 |
5 |
|
125 to 129 |
4 |
|
130 to 134 |
3 |
|
135 to 139 |
1 |
|
>= 140 |
0 |
gender |
male |
0 |
|
female |
4 |
sepsis |
no |
0 |
|
yes |
4 |
postoperative status |
no |
1 |
|
yes |
0 |
season |
spring |
1 |
|
summer |
0 |
|
fall |
3 |
|
winter |
1 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score:47
value of X =
= (0.21 * (score)) - 6.307
where:
• The original intercept was -6.58. The recalibrated intercept was - 6.58 + 0.273 = -6.307.
probability of severe vitamin D deficiency =
= 1 / ( 1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.85.
Specialty: Nutrition