The ISTHM (International Society on Thrombosis and Haemostasis) have proposed the concept of sepsis-induced coagulopathy (SIC). This overlaps with disseminated intravascular coagulopathy (DIC).
Parameters:
(1) INR
(2) platelet count per µL
(3) 4-item SOFA score (range 0 to 4)
Parameter
Finding
Points
INR
<= 1.2
0
1.2 to 1.4
1
> 1.4
2
platelet count
>= 150,000 per µL
0
100,000 to 149,999 per µL
1
< 100,000 per µL
2
4-item SOFA score
0
0
1
1
>= 2
2
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• A score >= 4 indicates SIC.
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