Levy et al reported the Seattle Heart Failure model for evaluation of a patient with heart failure. The authors are from multiple institutions in the United States and Europe.
Parameters:
(1) age in years
(2) sex
(3) NYHA class (from 1 to 4)
(4) left ventricular ejection fraction (LVEF) in percent
(5) ischemic heart disease as etiology for heart failure
(6) systolic blood pressure (SBP) in mm Hg
(7) diuretic therapy in mg/kg
(8) allopurinol therapy
(9) statin therapy
(10) serum sodium in mmol/L
(11) serum total cholesterol in mg/dL
(12) hemoglobin in g/dL
(13) percent lymphocytes in the differential count
(14) serum uric acid
(15) ACE inhibitor therapy
(16) beta blocker therapy
(17) angiotensin receptor blocker (ARB) therapy
(18) potassium-sparing diuretic
(19) implantable cardioverter device (ICD)
(20) body weight (BW) in kilograms
|
Parameter |
Finding |
Points |
|
age in years |
by decade |
0.08618 * ((age) / 10) |
|
sex |
female |
0 |
|
|
male |
0.08526 |
|
NYHA class |
|
0.47 * (NYHA class) |
|
ejection fraction |
|
100/(LVEF) * 0.02956 |
|
ischemic heart disease |
no |
0 |
|
|
yes |
0.30306 |
|
systolic blood pressure |
>= 160 mm Hg |
0 |
|
|
< 160 mm Hg |
-0.13125 * (SBP)/10 |
|
diuretic therapy |
no |
0 |
|
|
yes |
0.16382 * (mg/ (kg BW) |
|
allopurinol therapy |
no |
0 |
|
|
yes |
0.45171 |
|
statin therapy |
no |
0 |
|
|
yes |
-0.46204 |
|
serum sodium |
>= 138 mmol/L |
0 |
|
|
< 138 mmol/L |
0.04879*(138 - (sodium)) |
|
serum cholesterol |
|
0.79118 * (100/ (cholesterol) |
|
hemoglobin |
<= 16 g/dL |
0.11689 * (16 - (Hgb)) |
|
|
> 16 g/dL |
0.28968 * ((Hgb) - 16) |
|
percent lymphocytes |
|
-0.10870 * ((percent)/5) |
|
uric acid |
<= 3.4 mg/dL |
0 |
|
|
> 3.4 mg/dL |
0.06204*(uric acid) |
|
ACE inhibitor therapy |
no |
0 |
|
|
yes |
-0.26136 |
|
beta blocker therapy |
no |
0 |
|
|
yes |
-0.41552 |
|
ARB therapy |
no |
0 |
|
|
yes |
-0.16252 |
|
K-sparing diuretic |
no |
0 |
|
|
yes |
-0.3111 |
|
ICD |
no |
0 |
|
|
biventricular |
-0.23572 |
|
|
other |
-0.31471 |
where:
• The coefficients are based on LN(hazard ratio in
X =
= SUM(points for all of the parameters)
percent survival for 1 year =
= EXP((-0.0405 * EXP(X))
percent survival for 5 years =
= EXP((-0.0405 * 5 * EXP(X))
Specialty: Cardiology
