Walker et al reported a screening tool for late-onset neonatal bacteremia. This can help to identify a patient who may require more aggressive management. The authors are from Sunnybrook Health Science Centre and University of Toronto in Toronto, Canada.
Patient: neonate
Late-onset bacteremia: onset >= 72 hours after admission to NICU
Parameters:
(1) maximum blood glucose in mmol/L
(2) maximum heart rate in beats per minute
(3) percent bands in the differential count
(4) maximum absolute neutrophil count in 10^9/L
Parameter
Points
glucose
0.752 * (glucose)
heart rate
0.119 * (heart rate)
percent bands
0.108 * (percent bands)
absolute neutrophil count
0.071 * (count)
where:
• The heart rate is the main determinant of the final score.
value of X =
= SUM(poitns for all of the parameters) - 25.459
probability of bacteremia =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.89.
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