Description

Gallagher et al used the STOPP (Screening Tool of Older Person's Prescriptions) to help guide therapy in older adults. An important category are those used for patients with gastrointestinal or genitourinary disorders. The authors are from Cork University in Ireland.


 

Patient selection: age >= 65 years

 

Respiratory Drug

Comorbid

Other

Adverse Effect

theophylline monotherapy

COPD

 

safer alternative, narrow therapeutic index

systemic corticosteroids, long-term maintenance

moderate to severe COPD

 

adverse side effects of corticosteroids

nebulized ipatropium

glaucoma

 

glaucoma exacerbation

 

 

Endocrine Drug

Comorbid

Other

Adverse Effect

glibenclamide or chlorpropamide

type 2 diabetes

 

hypoglycemia

beta blockers

diabetes mellitus with hypoglycemic episodes

 

masking of hypoglycemic symptoms

estrogens

breast cancer

 

risk of cancer recurrence

estrogens

venous thrombo-embolism

 

risk of recurrent thrombosis

estrogens without progresterone

intact uterus

 

endometrial hyperplasia and cancer

 


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