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Screening for Anticholinergic Drug Toxicity Using Intravenous Physostigmine

Specialty:

Toxicology
Emergency Medicine
Critical Care

Objective:

ICD-10:

Description:

Sometimes it may be unclear if a patient has been exposed to an anticholinergic agent. Physostigmine is an anticholinesterase agent which normally produces cholinergic symptoms. Intravenous injection of a test dose of physostigmine can help separate those with anticholinergic drug intoxication from those who do not.

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