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Screening for a Urea Cycle Disorder Prior to Initiation of Valproic Acid Therapy

Specialty:

Endocrinology, Nutrition & Dermatology
Clinical Laboratory
Nephrology, Urology, Obstetrics & Gynecology, Pedatrics, Genetics

Objective:

ICD-10:

Description:

A patient with a urea cycle disorder (UCD) may develop hyperammonemic encephalopathy after starting valproic acid therapy. Prior to initiating valproic acid therapy a patient should be screened for clinical evidence of a possible urea cycle disorder.

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