Description

Perisse and Strickland developed an algorithm to screen a patient for malaria in a low-to-moderate transmission area. This may be particularly useful in a country with limited health-related resources. The authors are from the University of Maryland in Baltimore, Escola Nacional de Saude Publica in Rio de Janeiro, and the International Centre for Medical Research & Training in Lahore, Pakistan.


 

Parameters:

(1) history of fever

(2) headache

(3) myalgia

(4) back pain

(5) rigors

(6) cough

(7) nausea or vomiting

(8) splenomegaly (spleen palpated below the left costal margin on inspiration)

 

Parameter

Finding

Points

history of fever

absent

0

 

present

1

headache

absent

0

 

present

0.5

myalgia

absent

0.5

 

present

0

back pain

absent

0.5

 

present

0

rigors

absent

0

 

present

1

cough

absent

0.5

 

present

0

nausea or vomiting

absent

0

 

present

0.5

splenomegaly

not palpable

0

 

palpable

1.5

 

total score =

= SUM(points for all 8 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 6

• The higher the score the greater the likelihood of malaria.

 

Performance:

• A patient with a score >= 2 had a moderate sensitivity and specificity (varied with different times of the year and risk groups; sensitivity ranged from 40 to 70% and specificity ranged from 60 to 80%).

• A higher cutoff was more specific but less sensitive.

• Performance is impacted by the prevalence of malaria at the time.

 


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