Screening tests:
(1) anti-thyroglobulin antibodies
(2) anti-thyroid peroxidase antibodies
(3) TSH
Screening tests should be run:
(1) at initial diagnosis
(2) development of thyromegaly
(3) signs of hypo- or hyperthyroidism
(4) impaired linear growth in a pediatric patient
(5) periodically every 1-2 years
If the TSH is abnormal then consider measuring free T4 levels.
Consequences of hypothyroidism:
(1) reduced linear growth in pediatric patients
(2) hypoglycemia
Consequences of hyperthyroidism:
(1) difficult metabolic control
A patient with autoimmune thyroid disease may show antibodies to other endocrine organs as part of a polyendocrinopathy.
