A patient with growth hormone deficiency may have a number of problems that can result in a decreased quality of life (QOL). Rosen et al from the University of Goteborg in Sweden identified the most important problems faced by these patients. These can be easily screened for during a primary care visit.


Items to screen for:

(1) lack of energy (fatigue, low persistence)

(2) social isolation

(3) impaired sex life

(4) mood and personality disorders (depression, neurosis, phobias, immaturity, etc)

(5) economic problems (related to unemployment, taking disability or early retirement)


Responses can be given in various ways:

(1) present or absent

(2) major problem, minor problem, no problem

(3) none, mild, moderate, severe


A patient with one or more positive responses to screening questions should have a more in-depth analysis. This may include an endocrine evaluation to determine whether the growth hormone deficiency is part of panhypopituitarism.


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