Patient selection: pediatric patient with Kawasaki disease, maximum age 47 months
Parameters:
(1) age of the patient in years
(2) sex
(3) total fever duration
(4) IVIG resistance
(5) serum albumin in g/L
(6) percent monocytes in peripheral differential count
(7) delayed diagnosis (IVIG started after 10 days)
|
Parameter
|
Finding
|
All Patients
|
Age <= 0.5 Years
|
|
sex
|
female
|
0
|
0
|
|
|
male
|
1
|
0
|
|
total fever duration
|
< 8 days
|
0
|
0
|
|
|
>= 8 days
|
1
|
2
|
|
IVIG resistance
|
no
|
0
|
0
|
|
|
yes
|
1
|
0
|
|
serum albumin
|
> 35.9 g/L
|
0
|
0
|
|
|
<= 35.9
|
1
|
1
|
|
percent monocytes
|
< 5.9%
|
0
|
0
|
|
|
>= 5.9%
|
1
|
0
|
|
delayed diagnosis
|
no
|
0
|
0
|
|
|
yes
|
0
|
2
|
total score for all patients =
= SUM(points for 5 parameters assigned)
total score for a patient LTE 6 months old =
= SUM(points for all 3 assigned parameters)
Interpretation:
• minimum scores: 0
• maximum score for all patients: 5
• maximum score for patient LTE 6 months: 5
• The cutoff for the patient LTE 6 months was >= 3.
Performance:
• The area under the ROC curve for a patient LTE 6 months old is 0.73. The sensitivity at ctoff was 0.65 and specificity 0.81.
• The area under the ROC curve for all patients was 0.63. At a cutoff of >=2 the sensitivity was 0.83 and specificity 0.34.
