Score of Xu et al for a Patient with Aplastic Anemia Following a Haploidentical Allogeneic Hematopoietic Stem Cell Transplant (Haplo-HSCT Scoring System)
Xu et al reported a predictive score for a patient with aplastic anemia who has undergoing a halpoidentical allogeneic hematopoietic stem cell transplant. This can help to identify a patient who may require more aggressive therapy. The authors are from Peking University of Beijing.
Patient selection: aplastic anemia, status post haploidentical allogeneic hematopoietic stem cell transplant (HSCT)
Parameters:
(1) time from diagnosis of aplastic anemia to HSCT in months
(2) ECOG performance status before HSCT
(3) hematopoietic cell transplantation-specific comorbidity index (HCT-CI) before HSCT, from 0 to 26
Parameter
Finding
Points
time from diagnosis
< 12 months
0
>= 12 months
1
ECOG performance
0 or 1
0
2 to 4
1
HCT-CI before HSCT
0
0
>= 1
1
total score =
= SUM(points for the 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
Score
Risk Group
3-Year Treatment Related Mortality
0 or 1
low
6%
2
intermediate
21%
3
high
47%
To read more or access our algorithms and calculators, please log in or register.
