Urbina et al identified risk factors for potential drug-related problems in hospitalized patients. The authors are from Hospital Universitari del Mar in Barcelona.
Parameters:
(1) age
(2) Charlson comorbidity index
(3) number of drugs during hospitalization
(4) major diagnostic categories
(5) Anatomic Therapeutic Chemical (ATC) classification
|
Parameter |
Finding |
Points |
|
age |
<= 60 years |
0 |
|
|
> 60 years |
1 |
|
Charlson Comorbidity Index |
0 or 1 |
0 |
|
|
2 |
1 |
|
number of drugs |
<=10 |
0 |
|
|
> 10 |
3 |
where:
• The CCI will be implemented as >= 2.
Points for major diagnostic categories – 1 point for each present:
(1) nervous system
(2) circulatory system
(3) digestive system
(4) musculoskeletal system and connective tissue
(5) kidney and urinary system
(6) others
|
ATC group |
Points if Present |
|
cardiovascular (C) |
1 |
|
hormone therapy (H) |
1 |
|
systemic anti-infective (J) |
1 |
|
sensory organs (S) |
2 |
|
various (V) |
2 |
total score =
= SUM(points for all of the parameters present)
Interpretation:
• minimum score: 0
• maximum score: 18
• The higher the score the greater the risk of a drug-related problem.
|
Score |
Percent with Drug-related Problem |
|
0 |
1 to 3% |
|
1 or 2 |
8 to 11% |
|
3 or 4 |
16 to 21% |
|
5, 6 or 7 |
32 to 41% |
|
>= 8 |
51 to 61% |
Performance:
• The area under the ROC curve was 0.78.
Specialty: Toxicology, Emergency Medicine, Critical Care
ICD-10: ,
