Score of Sujan et al for Acute Kidney Injury in a Patient with Alcoholic Hepatitis (AKI-AH Risk Score)

Description

Sujan et al developed a score for determining the risk of acute kidney injury (AKI) in a patient with alcoholic hepatitis (AH). Acute kidney injury negatively impacts short-term survival. The authors are from the University of Alabama, Universidad Nacional Autonoma de Mexico, Vall d'Hebron University, the Mayo Clinic, Institute of Liver and Biliary Sciences New Delhi and the University of Pittsburgh.

Patient selection: alocholic hepatitis

Parameters:

(1) MELD score

(2) hepatic encephalopathy (HE)

(3) systemic inflammatory response syndrome (SIRS)

Parameter	Finding	Points
MELD		MELD * LN(1.109) = MELD * 0.1
hepatic encephalopathy	absent	0
	present	LN(2.775) = 1.02
SIRS	absent	0
	present	LN(1.993) = 0.69

where:

• LN(odds ratio) generates the logistic regression coefficient.

AKI AH risk score =

= SUM(points for all 3 parameters)

Interpretation:

• The higher the AKI AH the greater the risk for acute kidney injury and the worse the short-term survival.

AKI AH Score		90-Day Survival
< 3	low risk	88%
3 to 4	moderate risk	68%
> 4	high risk	47%

Performance:

• The area under the ROC curve is 0.76.

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Score of Sujan et al for Acute Kidney Injury in a Patient with Alcoholic Hepatitis (AKI-AH Risk Score)

Description

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